In the future, you may able to take oral vaccine in the form of capsule for coronavirus also. Several pharmaceutical companies have been developing oral vaccines all over the world at the moment. Latest oral vaccine for coronavirus is being developed by an Indian pharmaceutical company called Premas Biotech.
On the occasion, Premas Biotech has collaborated with an American company called Oramed Pharmaceuticals Inc. The development about the oral COVID-19 vaccine as capsule has been announced on 19th March. Through a single dose of oral vaccine, efficacy against the coronavirus is expected to be seen also.
During a pilot study on the animal, single dose of oral coronavirus vaccine called Oravax has shown its effectiveness, Systematic immunity is expected to be offered by the Oravax vaccine. It is expected to create neutralizing antibodies in addition to immune response in order to protect both the gastrointestinal tract and respiratory system from the possible chances of infection.
Technique
For Premas Biotech oral vaccine, protein based VLP which is also known as ‘Virus Like Particle’ is going to utilized to offer triple protection. On the occasion, protection can be provided against Spike S protein, Envelope E and Membrane M of SARS CoV-2.
Background
Dr. Prabuddha Kundu is co-founder and also managing director of Premas Biotech. By using the D-Crypt platform of proprietary nature from Premas Biotech, VLP vaccine is going to be made. On the other hand, Oramed has been offering the world leading delivery platform POD for oral protein.
By the oral vaccine Oravax, benefits of two exclusive platforms are going to combined and harnessed.
So far, preliminary results have been seen only following to the studies on animals. Soon, clinical trial of the oral vaccine Oravax is going to begin. According to the schedule, clinical trial may start from the second quarter of this year.
Bharat Biotech is also trying to create a nasal vaccine for coronavirus in collaboration with the University of Wisconsin. Clinical trial for this vaccine has started. Even, human stage trial has begun in India for this nasal vaccine.
Till now, Serum Institute’s Covishield and Bharat Biotech’s Covishield are allowed for use in India. In American, people are being vaccinated with Pfizer and Moderna vaccine in addition to the AstraZeneca vaccine. These vaccines are being used for immunization in Europe and some other parts of world also. In addition, there is also Russia’s Sputnik V vaccine.
Through use of vaccine, people have been trying to rise above the coronavirus and stay safe.
